For healthcare professionals. This information does not replace clinical judgement in the individual case; the current summary of product characteristics and the guidelines cited are authoritative.
Medically reviewed: Dr. med. univ. Daniel Pehböck, DESA, 01.11.2026
Prothrombin complex concentrate (PCC) (Coagulation factor concentrate (factors II, VII, IX, X, protein C/S; plasma-derived)) – indications: Reversal of vitamin K antagonist (bleeding, emergency surgery), Life-threatening bleeding on a factor Xa inhibitor (off-label). Weight-based dosing in mg and ml in the app, with sources.
Indications
- Reversal of vitamin K antagonist (bleeding, emergency surgery)
- Life-threatening bleeding on a factor Xa inhibitor (off-label)
Complete in the app
Weight-based doses in mg and ml, preparations, contraindications and notes – in the app, also offline.
Used in
Sources and guidelines
- Rossaint R, Afshari A, Bouillon B et al. The European guideline on management of major bleeding and coagulopathy following trauma.
- Christensen H, Cordonnier C, Kõrv J et al. European Stroke Organisation Guideline on Reversal of Oral Anticoagulants in Acute Intracerebral Haemorrhage. Eur Stroke J 2019;4(4):294–306.
- Summaries of product characteristics of authorised products – product and section for each dose in the app.