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Sodium bicarbonate

Buffer / alkalinising agent; antidote for sodium-channel-blocking agents

For healthcare professionals. This information does not replace clinical judgement in the individual case; the current summary of product characteristics and the guidelines cited are authoritative.

Medically reviewed: Dr. med. univ. Daniel Pehböck, DESA, 01.11.2026

Sodium bicarbonate (Buffer / alkalinising agent; antidote for sodium-channel-blocking agents) – indications: Cardiac arrest due to hyperkalaemia – adults, Tricyclic antidepressant / sodium channel blocker poisoning – adults, Tricyclic antidepressant / sodium channel blocker poisoning – children, Severe metabolic acidosis (guided by blood gas analysis). Weight-based dosing in mg and ml in the app, with sources.

Indications

  • Cardiac arrest due to hyperkalaemia – adults
  • Tricyclic antidepressant / sodium channel blocker poisoning – adults
  • Tricyclic antidepressant / sodium channel blocker poisoning – children
  • Severe metabolic acidosis (guided by blood gas analysis)

Complete in the app

Weight-based doses in mg and ml, preparations, contraindications and notes – in the app, also offline.

Used in

Sources and guidelines

  1. Lott C et al. European Resuscitation Council Guidelines 2025: Special Circumstances in Resuscitation. Resuscitation 2025;215 Suppl 1:110753.
  2. Tox Info Suisse. Antidot-Monographie Natriumhydrogenkarbonat.
  3. ToxInfo (toxinfo.de). Antidote im Detail.
  4. Summaries of product characteristics of authorised products – product and section for each dose in the app.