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Lipid emulsion 20 %

Antidote for local anaesthetic systemic toxicity (LAST) – off-label

For healthcare professionals. This information does not replace clinical judgement in the individual case; the current summary of product characteristics and the guidelines cited are authoritative.

Medically reviewed: Dr. med. univ. Daniel Pehböck, DESA, 01.11.2026

Lipid emulsion 20 % (Antidote for local anaesthetic systemic toxicity (LAST) – off-label) – indications: Local anaesthetic systemic toxicity (LAST) with circulatory instability or cardiac arrest. Weight-based dosing in mg and ml in the app, with sources.

Indications

  • Local anaesthetic systemic toxicity (LAST) with circulatory instability or cardiac arrest

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Weight-based doses in mg and ml, preparations, contraindications and notes – in the app, also offline.

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Used in

Sources and guidelines

  1. Neal JM, Neal EJ, Weinberg GL. American Society of Regional Anesthesia and Pain Medicine Local Anesthetic Systemic Toxicity checklist: 2020 version. Reg Anesth Pain Med 2021;46:81–82.
  2. Association of Anaesthetists of Great Britain and Ireland (AAGBI). Safety Guideline: Management of Severe Local Anaesthetic Toxicity. London 2010.